We would not be pursuing spiritual subjects or meditation practice unless we wanted to change. Today we begin the topic of what it feels in the body and mind when we are changing inside. This is not just signs of inner spiritual development, as though we were becoming holier every day. The physical and mental changes produce practical and important influence on other areas of life. How we are changing our perceptions by meditation and living by Buddhist principles, changing our minds about what is truth, and seeking reality bears on what kind of career we choose and what kind of relationships we desire to have with others. Spiritual inner change has effects in the physical body, brain, and mental functions that are energetic, chemical, and emotional. In Tibet, we did not discuss change in this way because we have a medical system that explains disease or mental difficulties as imbalances of the three humors and how that affects the mind and body. It also describes how meditation